Class 3

How Yamanaka's Lab assistant discovered the 4 factors (Oct4,Sox2,Klf4, and cMyc) aka OSKM, from the 24 original number: click here
Video of today's class: click here
This is a short video of transcription and translation of mRNA to protein: click here





Operons for plasmids: click here
More about tet-on and tet-off than you would ever want to know: click here
What are Pluripotent Stem Cells?



How does methylation prevent genes from transcribing?

CpG methylation increases with age (epigenes)

Here's a short history of recent progress in ageing: click here
The role of the mitochondria in ageing with David Sinclair: click here
The role of the hypothalamus in ageing with Dr Dongsheng Cai: click here
Here is Yamanaka explaining how we can use stem cells to cure diseases: click here
How stem cells are collected and stored: click here
Shai Efrati, Israeli physician, explains the theory of hyperbaric therapy: click here
David Sinclair recently explains how his lab repaired mouse vision using Yamanaka stem cell technology: click here
Steve Horvath (jan 2021) describes regression with Yamanaka factors: click here